منابع مشابه
Ferns and Heikal, Atherogenesis and hypoxia Hypoxia in Atherogenesis
The anoxemia theory proposes that an imbalance between the demand for, and supply of, oxygen in the arterial wall is a key factor in the development of atherosclerosis. There is now substantial evidence that there are regions within the atherosclerotic plaque in which profound hypoxia exists; this may fundamentally change the function, metabolism and responses of many of the cell types found wi...
متن کاملHypoxia in Atherogenesis.
The anoxemia theory proposes that an imbalance between the demand for and supply of oxygen in the arterial wall is a key factor in the development of atherosclerosis. There is now substantial evidence that there are regions within the atherosclerotic plaque in which profound hypoxia exists; this may fundamentally change the function, metabolism, and responses of many of the cell types found wit...
متن کاملHypoxia, Angiogenesis and Atherogenesis
The balance between vascular oxygen supply and metabolic demand for oxygen within the vasculature is normally tightly regulated. An imbalance leads to hypoxia and a consequential cascade of cellular signals that attempt to offset the effects of hypoxia. Hypoxia is invariably associated with atherosclerosis, wound repair, inflammation and vascular disease. The anoxaemia hypothesis proposes that ...
متن کاملVisceral white fat remodelling contributes to intermittent hypoxia-induced atherogenesis.
Obstructive sleep apnoea is a highly prevalent disease characterised by repetitive upper airway collapse during sleep leading to intermittent hypoxia. Cardiometabolic complications of sleep apnoea have been mostly attributed to intermittent hypoxia. These consequences could be mediated through intermittent hypoxia-related alterations of the visceral white fat, as it is recognised for playing an...
متن کاملVisceral white fat remodeling contributes to intermittent hypoxia-induced atherogenesis
Objective: Obstructive sleep apnea is a highly prevalent disease characterized by repetitive upper airway collapse during sleep leading to intermittent hypoxia. Cardio-metabolic complications of sleep apnea have been mostly attributed to intermittent hypoxia. These consequences could be mediated through intermittent hypoxia-related alterations of the visceral white fat, as it is recognized for ...
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ژورنال
عنوان ژورنال: Angiology
سال: 2016
ISSN: 0003-3197,1940-1574
DOI: 10.1177/0003319716662423